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Canonical pyroptosis is triggered by pattern recognition receptors ( e.g

Diagnosis and management of the metabolic syndrome: an American heart association/National Heart, Lung, and Blood Institute Scientific Statement

Of note the prolonged treatment with BSO did not substantially affect the weight of treated mice, suggesting limited undesired effects associated with this regimen

Moreover, only 54% of patients in those economics have access to oral cysteamine therapy, and there is limited access to cysteamine eye drops, supportive therapies, and standard diagnostic and monitoring tools, all of which are essential for the prevention of disease progression and extended lifespan [159]

doi: 10.1002/fsn3.962, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 92.stn N, Bulam S, Peken A