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Hasan SS, et al

Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation

Seizure 2001;10:116-119

Ringseis, R., Keller, J., and Eder, K.: Regulation of carnitine status in ruminants and efficacy of carnitine supplementation on performance and health aspects of ruminant livestock: A review, Arch

Importantly, in these experimental models, pre-hypoxic treatment with sodium 2-[5-(4-chlorophenyl)-pentyl]-oxirane-2-carboxylate (POCA) or oxfenicine, both inhibitors of CPT I, prevents membrane and cytosolic LCAC accumulation in early ischaemia and the genesis of electrophysiological derangements (Yamada et al., 1994)
