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Description
Unexpected histone H3 tail-clipping activity of glutamate dehydrogenase
BPC-157 (Body Protection Compound-157) is a synthetic peptide fragment derived from a naturally occurring protein found in gastric juice
It has been demonstrated in melanoma cell lines that the direct transcriptional target of TGF-1-the Kruppel-like transcription factor GLI2 not only suppresses MITF through PKA/cAMP signaling 52 but also directly downregulates tyrosinase-related protein 2 (TRP2) by competitive inhibition of CREB 53
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, & Cukrowska, B
