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An Updated Systematic Review with Meta-Analysis for the Clinical Evidence of Silymarin

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Thus, multiple factors bring about the altered intercellular communication, one of which (the SASP) is directly triggered by the cellular senescence

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They also boost the healing process by promoting tissue repair and stimulating the production of collagen

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Research by Nederlof et al (79) suggests that IGF-1 can also modulate neutrophil function by enhancing the phosphorylation of STAT6, polarizing neutrophils towards the anti-inflammatory N2 phenotype through activation of the atypical downstream Janus kinase (JAK)-STAT pathway, thereby promoting an anti-inflammatory response

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