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Additionally, rare deficiencies of glutathione cycle enzymes (gamma-glutamylcysteine ligase, glutathione synthetase, 5-oxoprolinase, and gamma-glutamyl transferase) have all been associated with neuropsychiatric and cognitive impairments, although detailed phenomenological characterization has not been reported (9, 61, 62)

In a 2019 study evaluating women with polycystic ovary syndrome (PCOS) who were overweight or obese, a combination of diet and myo-inositol (MI) and folic acid or a diet with MI and D-chiroinositol (DCI) accelerated weight loss and reduced fat mass

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