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As epigenetic modifications are reversible, the molecules that can target the enzymes involved in these mechanisms may be good drug candidates to fix these alterations and subsequently restore normal gene expression

The blood selenium level of cancer patients is lower than normal, and the cancer mortality rate is also negatively correlated with the blood selenium level (Zou et al., 2002)

M., Kester, M

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While numerous animal studies ( in vivo ) show significant effects on hormone levels and immune parameters, clinical trial data in humans remains limited for most interventions