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Figure 8 4 Discussion Pro-inflammatory cytokines, TNF- and IL-6, have been linked to numerous CNS disorders including neurodegenerative diseases, autism spectrum disorder, psychiatric disorders, and more recently cognitive impairment associated with long-COVID (Lucas et al., 2006

K.LiH.GummuluruS.et al (2014)

from 5 to 95% phase B at 115.00 min

TLRs signaling modulations Toll-like receptors (TLRs) are pivotal pattern recognition receptors that detect microbial components and host-derived danger-associated molecular patterns (DAMPs) at the wound site, initiating innate immune responses essential for infection control and tissue repair

VidalAlaball J, Butler C, CanningsJohn R, Goringe A, Hood K, McCaddon A, McDowell I, Papaioannou A
