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Using the combinations of stable isotope ( 13 C) tracers, NMR and GCMS profiling, and isotopomer spectral analysis (ISA), we found that APAP-treated HepG2 cells exhibit an enhanced Warburg effect, in that lactate production from glucose exceeded the already elevated levels of cancer cells, leading to rapid depletion of glucose from the media

Because glutathione is the major intracellular antioxidant defense within a cell, it is proposed that its depletion might be a prerequisite for modulating the apoptotic machinery in autoimmune disease like SLE

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The modified GPx-DTNB method showed a linear range of 21000 U.L 1 of GPx activity, with a high degree of linearity (Pearson's r value of 0.999) and sensitivity (LOQ of 1 U.L 1 and LOD of 3 U.L 1 )
