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[3] Cell Line:RBL-2H3 cells, human LAD2 mast cells Concentration:15 M Incubation Time:1 h Result:Inhibited S1P secretion by vector and SphK1 transfected RBL-2H3 cells, whereas it did not affect uptake and intracellular conversion of [3H]Sph to S1P

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Phenolic compounds exhibit a anti-genotoxic activity with many mechanisms such as inhibition of promutagens, induction of detoxification mechanism, blocking of free radicals, scavenging of reactive oxygen species, and neutralization of oxidative stress and inhibition of DNA cleavage 66
