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The chelation and reduction capabilities of flavonoids are largely attributed to their functional groups, particularly carbonyl and hydroxyl moieties, which facilitate metal ion binding at multiple sites

In nonalcoholic steatohepatitis (NASH), MGO exacerbates insulin resistance and metabolic disorders, leading to increased AGE formation and disease progression [168]

Autosomal dominant iron overload due to a novel mutation of ferroportin1 associated with parenchymal iron loading and cirrhosis

, Kamitori, K

Hyperglycemia and IR are responsible for worsening S aggregation and mitochondrial dysfunction, both of which contribute to the loss of dopamine-producing neurons