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Furthermore, the complexity of HIV-1 is compounded by the existence of numerous viral subtypes that vary across different geographical regions

Ralph Carmel, one of the leading researchers on vitamin B12, published a study in 1988 with several subjects analyzed, suggesting a relationship between higher amounts of accumulated analogues and a greater risk of neurological symptoms, which could explain why some patients did not experience neurological symptoms (at least at the time) but did experience anemia