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The model predicted that for 10-hour-long toxicologically relevant doxorubicin (50 M) simulations, the duration of the exposure is more important than concentration with respect to overwhelming glutathione metabolism
Reversible inactivation of the tumor suppressor PTEN by H2O2
Proteins were separated using a 35 min gradient running 0.1% formic acid (eluent A) against 80% acetonitrile with 0.1% formic acid (eluent B) at a constant flow of 600 nl/min
Musunuru K, Grandinette SA, Wang X, Hudson TR, Briseno K, Berry AM, et al
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