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Description
The 5-LOX enzyme, found in CD163 + tumor-associated macrophages, promotes the formation of hepatocellular carcinoma (HCC) by generating leukotrienes that augment cancer cell proliferation and stem cell capabilities [275]
This aligns with current mainstream research
10.1007/s11064-008-9782-x 15
Chandra S, Radwan MM, Majumdar CG, Church JC, Freeman TP, ElSohly MA
Melatonin Melatonin is derived from serotonin within the pineal gland and the retina, where the rate-limiting enzyme for melatonin synthesis is expressed
