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[DOI] [PubMed] [Google Scholar] Mayatepek E., Nezu J., Tamai I., Oku A., Katsura M., Shimane M., Tsuji A

Pharmacological treatment of chemotherapy-induced neuropathy: a systematic review of randomized clinical trials
Maintaining muscle tissue takes four to five times more calories than maintaining fat tissue, which is important for permanent weight loss

It results in adrenergic stimulation, leading to thermogenesis and lipolysis, eventually promoting energy expenditure and fat oxidation

The combination with another antidepressant such as milnacipran did not show superiority compared to treatment with PGB alone [15]
