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In preclinical anti-tumor research, acridine acriflavine (ACF), a long-used anti-parasite and antibacterial antibiotic, is utilized to block HIF, EMT, p53 activation, and mitochondrial or endoplasmic reticulum autophagy

Landscapes Health & Medical Sciences (AREA) Chemical & Material Sciences (AREA) Medicinal Chemistry (AREA) Pharmacology & Pharmacy (AREA) Epidemiology (AREA) Life Sciences & Earth Sciences (AREA) Animal Behavior & Ethology (AREA) General Health & Medical Sciences (AREA) Public Health (AREA) Veterinary Medicine (AREA) Medicinal Preparation (AREA) Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA) Abstract An improved method for delivery of glutathione, a major intracellular antioxidant, by oral administration of S-acetyl-glutathione (SAG) is provided

doi: 10.1117/1.JBO.21.5.050901 80 WatsonJRMartirosyanNLemoleGMTrouardTPRomanowskiM

The prevalence of melasma can be varied from 1% in the normal population to 50% in the high-risk population

PMID: 6183535