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4.3 Cancer 4.3.1 Oxidative stress increases cancer risk Numerous research has indicated that tumors produce a higher amount of ROS compared to healthy cells

[DOI] [PubMed] [Google Scholar] 294.Somodi S., Varga Z., Hajdu P., Starkus J.G., Levy D.I., Gaspar R., Panyi G

Excessive alcohol consumption is considered a risk factor for the development of cancer in the upper gastrointestinal tract, because of exposure to acetaldehyde, which is carcinogenic to humans

doi: 10.1179/1351000212Y.0000000036

The results suggest that the deficiency of SAMe, probably together with other factors related to Mat1a deficiency, contributes to the increased translocation of NRF2 to the nucleus