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Kruis, T., Batra, A

Additionally, reducing visceral fat can lower the risk of heart disease by promoting heart-healthy eating, controlling hypertension, and encouraging physical activity

If NNMT inhibition both restores adipocyte energy expenditure (promoting fat reduction) and supports myogenic differentiation (preserving or enhancing muscle), the net body composition effect could be recomposition simultaneous fat loss and lean mass preservation

Rewiring of the metabolic pathways of glutamine and other amino acids is thought to be an important bioenergetic adaptation in OXPHOS-defective cells or cancer cells