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In addition, the monomethyl branched-chain fatty acid C17iso could ensure the integrity of the ER membrane, whose biosynthesis requires the acyl coenzyme A synthase encoded by fatty acid CoA synthetase-1 ( acs-1 ), thereby maintaining the function of ER-resident enzymes for an appropriate lipid synthesis and the growth of LDs [46]
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Serotonin and 5-HT receptor agonist treatment of DP cells A suspension of DP cells (2 10 4 cells) in 0.5 mL DPCGM was seeded into a 24-well culture plate (Corning Inc., Corning, NY, USA)
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10.1038/nri3520 87 MoraS.BuringJ
