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[DOI] [PubMed] [Google Scholar] 18.Siegfried JM, Kasprzyk PG, Treston AM, Mulshine JL, Quinn KA, Cuttitta F

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These methods involve the use of mitochondrially-targeted compounds (e.g., oligomycin, FCCP) in conjunction with the measurement of oxygen consumption rate to assess mitochondrial respiration parameters (Seahorse XFp analyzer technology) [39, 62, 63], as well as high-resolution respirometry to evaluate mitochondrial oxidative phosphorylation (OXPHOS) capacity with complex I + II-linked substrates (Oroboros O2k-technology) [42]

Protective effect of carnosic acid against paraquat-induced redox impairment and mitochondrial dysfunction in SH-SY5Y cells: Role for PI3K/Akt/Nrf2 pathway