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Other metabolites that might be involved in SARS-CoV-2 replication are related with the purine metabolism, and it has been suggested that SARS-CoV-2 remodels host folate and one-carbon metabolism to support de novo purine synthesis 41

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J Gerontol A Biol Sci Med Sci 61(7):663674 Clavel S, Coldefy AS, Kurkdjian E, Salles J, Margaritis I, Derijard B (2006) Atrophy-related ubiquitin ligases, atrogin-1 and MuRF1 are up-regulated in aged rat Tibialis Anterior muscle