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10.1016/j.febslet.2004.08.084 146 RoosensN

Compared to curcumin itself, the biological effectiveness of curcumin metabolites, excluding 4HC, is considerably reduced (82, 116)

However, this theory is in dispute because through in vitro techniques using microfluidic chambers, Gornstein and Schwarz have recently found that the distal part of the axon is selectively sensitive to PCTX (Gornstein and Schwarz, 2017)

S.BorchersC.BrierS.et al (2019)

2 With regard to side effects, oral or inhaled NAC has been associated with drowsiness, stomatitis, clamminess, rhinorrhea, and hemoptysis
