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However, during pyrimidine biosynthesis, a 1C unit is used in methylation reactions using methylene-tetrahydrofolate (methylene-THF) as the methyl donor, where deoxyuridine monophosphate (dUMP) is converted to deoxythymidine monophosphate (dTMP) with the help of thymidylate synthase (TYMS) [53]
10.1016/j.celrep.2019.02.037 119 LuT.LiM.ZhaoM.HuangY.BiG.LiangJ.et al (2021)

American Journal of Clinical Nutrition , 117 , 477489

Most practitioners prefer the no DAC version because its more physiologic and allows easier dose adjustment

BPC 157 works in different ways
