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5.2.4 Ferroptosis suppressor protein 1 and coenzyme Q10 pathway FSP1 possesses NAD(P)H oxidoreductase activity and reduces CoQ to ubiquinol (CoQH2), which inhibits lipid peroxidation and ferroptosis by trapping lipid peroxidation free radicals (77, 78)

Milani ZH, Ramsden DB, Parsons RB (2013) Neuroprotective effects of nicotinamide N -Methyltransferase and its Metabolite 1-Methylnicotinamide

No genotoxicity, mutagenicity, or organ-specific toxicity was reported at the doses tested in the preclinical safety evaluation

Nature 530 , 447 (2016)

A study endeavored to evaluate the potential of selenium supplementation to decelerate the progression of prostate cancer by administering daily doses of selenium to patients with prostate-specific antigen (PSA) indicative of prostate cancer (108)
