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Retatrutide's Phase 2 trial data (Jastreboff et al., NEJM 2023) identified a side-effect profile broadly consistent with other incretin-based therapies: Gastrointestinal : Nausea, vomiting, diarrhoea, and constipation were the most commonly reported adverse effects, particularly during dose escalation

Finally, it decreases ulcers and infections in bone, liver, lung connective tissue, skin, and the stomach lining

AOD 9604 affects fat metabolism by targeting specific biochemical pathways that regulate how the body stores and breaks down fat

Before we dive into how they work together, lets understand what each of these nutrients does on its own

Nov 2013;27(6):435-437