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Conjugates of cisplatin and cyclooxygenase inhibitors as potent antitumor agents overcoming cisplatin resistance

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250252 Biological Assays for the Identification of NOX Inhibitors The evaluation of the activity of potential NOX inhibitors is generally performed by applying different enzymatic assays based on the measurement of substrates (i.e., NADPH or O 2 ) and/or reactive oxygen species (i.e., superoxide anion and H 2 O 2 ) that are consumed and/or generated by NOX proteins

Some suggest splitting doses, others insist on single morning administration

Reduced glutathione levels improved in erythrocytes, plasma, lymphocytes and buccal cells in only 1 month