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16 Ivacaftor stabilizes the open state of CFTR, thus increasing chloride transport of wild-type CFTR and stimulates the activity of G551D-CFTR to 50% of that of non-mutated CFTR
All clinical trials with this product are being conducted or will be conducted under the supervision of other clinicians at sites other that the Academic Medical Center where Dr
Wang X, Morris-Natschke SL, Lee KH
A handful of other companies have tau-targeting antibodies in earlier phases
