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Additionally, due to its participation in the CD38/CD203a/CD73 adenosinergic pathway, CD38 has been identified as an effective predictor of anti-PD-1 antibody-based checkpoint immunotherapy responses (49)

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Nociceptive pain, also referred to as receptor pain, arises from tissue damage due to activation of pain receptors (nociceptors) Nociceptive pain can be further subdivided into deep somatic pain, associated with activation of nociceptors in muscles, tendons, ligaments, bones, or lining tissues such as the peritoneum

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