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The retinal pathology of AMD patients demonstrates that cholesterol is enriched in these deposits, suggesting that dysregulation of cholesterol homeostasis may contribute to AMD pathogenesis (Curcio et al., 2005

In a previous study, high concentrations of iron and cadmium increased oxidative stress in the seminal plasma and sperm homogenate of the infertile group, decreased the content of antioxidants, and thus had a strong toxic effect on spermatogenesis by producing excessive oxidants and inducing apoptosis (14)

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A., Sugiana, C., Boneh, A., Chen, W