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The spectrum of myopathies ranges from predominantly muscle disorders such as the muscular dystrophies, congenital myopathies, and myositis to multisystem disorders with muscle tissue involvement such as metabolic myopathies and myotonic dystrophy

L-carnitine deficiency has been demonstrated to reduce the availability of energy in the liver and is associated with impairments in various aspects of energy metabolism, including utilization and accumulation of carbohydrate and lipids in liver cirrhosis (7,8)

30 , 31 Since ()-huperzine A (1) inhibits AChE 50-fold more efficiently than the (+)-enantiomer ent -1, the relationship between absolute stereochemistry and attenuation of A toxicity has been studied

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