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The Methionine Cycle As indicated above, the methionine cycle is the central aspect of the methylation cycle and is therefore sometimes referred to as the methylation cycle alone

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J Neural Transm 121:12691272 [DOI] [PubMed] [Google Scholar] Liu D, Ke Z, Luo J (2017) Thiamine deficiency and neurodegeneration: the interplay among oxidative stress, endoplasmic reticulum stress, and autophagy

Hydroxocobalamin is also used to detoxify cyanide in the body, which makes it a unique choice for individuals exposed to cyanide

Deficiency can lead to anemia, nervous system damage, and fatigue, making it essential for those on a vegan or vegetarian diet to find reliable B12 sources