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Chi-square and logistic regression were used to assess vitamin C use in relation to clinicopathological features in univariable and multivariable models

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Specifically, phosphorylation of PTEN at Ser380 (within the C-terminal tail cluster) is generally regarded as a stabilizing but inhibitory modification, reducing its lipid-phosphatase activity and thereby facilitating PI3K/AKT pathway activation [69, 70]

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