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Discussion Significantly increased cortisol concentrations in the serum of the studied men after 8 days of water-only fasting and maximum physical exercise indicate the stimulation of a strong stress reaction, which was activated mainly by the fasting intervention

It is a long-acting ester used for testosterone replacement therapy to treat low testosterone (hypogonadism) and is also used in bodybuilding for muscle mass and strength gains

This precision nutrition-based dietary rehabilitation of PASC patients should be developed as an affordable, interventional regimen for divergent socio-economic populations worldwide for effective public health management of any future emergence of virus-induced new onset human metabolic syndromes

Current research has focused primarily on key metabolic pathways and molecules such as mTOR, AMPK, and HIF-1, with many targets for metabolic therapy under early stages of investigation in preclinical studies or clinical trials