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Such defects occur early in pregnancy and affect brain and spinal cord development

Temporary urine discoloration (bright yellow), which is harmless

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May be a marker of underlying disease (e.g., liver disease, malignancy, MDS/CML)

Patients with a history of pancreatitis should be evaluated carefully before initiating treatment with Semaglutide / Cyanocobalamin Injection, as GLP-1 receptor agonists have been associated with acute pancreatitis in post-marketing surveillance, though a definitive causal relationship has not been established