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The bodys defense against oxidative stress relies on antioxidant mechanisms governed by nuclear factor erythroid-2-related factor 2 (Nrf2), which regulates enzymes like superoxide dismutase (SOD) and catalase (CAT)

Following HFD feeding, the increases in glutamine-to-glutamate ratio and lactate levels, elevated energy expenditure as well as iWAT browning were retained in Gls AdipoqCre mice (Fig

Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A

4.5 Rheumatoid arthritis Rheumatoid arthritis (RA) is an inflammatory disease produced by immune impairment, which causes joint swelling, stiffness, and disfeature and dysregulates joint function