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In parallel, glycolysis inhibition increased cell death in Gclc -deficient FoB to a stronger extent when compared to controls (Fig

To investigate the observed dual degradation of AR, AR-V7 and HSP90 at the cellular level, we comprehensively evaluated the downstream pharmacodynamic outcomes and cytotoxic efficacy

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Therefore, based on meta-analyses of clinical trials, at present, no drug can be proposed as a gold standard to either prevent CIPN or treat its symptoms, and chemotherapeutic drug dose modification remains the only preventative strategy [41]

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