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On the other hand, JHU083-treated NSG mice showed minimal therapeutic benefit when compared with JHU083-treated RAG1-KO and WT mice in the early and late phases of tumor growth (Figure 1G)

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10.3390/ph12020093 Pharmaceuticals 95 MathysH.Davila-VelderrainJ.PengZ.GaoF.MohammadiS.YoungJ

These findings demonstrate that the downregulation of CINC-3 expression mediated by DP likely constitutes a key mechanism underlying its attenuation of neuroinflammation and neuropathic pain
