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However, the overall contribution of the CntA-mediated conversion of L-carnitine has been controversial in the context of microbiome investigations ( cntA gene directly correlates with substantial L-carnitine metabolism and the formation of TMA

A.FrzouI.GriselP.BaptistaS.LowD.et al (2019)

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Fumaric acid, bound to L-carnitine, also occurs naturally as an intermediate product in the citric acid cycle