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This paradigm shift from cell replacement to trophic support and immunomodulation is critical, as it suggests that functional recovery can be achieved by improving the pathological microenvironment that contributes to neuronal dysfunction and death

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Additionally, SELENOP expression was most robust in the choroid plexus and regions lining the brain ventricles (Sasuclark et al., 2019), which is in line with the previous studies (Rueli et al., 2015)

doi: 10.1123/ijsnem.22.1.64
