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We examined the effect of primary human CAFs on p53 induction and cell viability in prostate cancer cells on treatment with chemotherapeutic drugs

Recognized mechanisms include oxidative stress, mitochondrial dysfunction, neuroinflammation, insulin resistance, and protein misfolding

utilized a six-month course of NAC supplementation in diabetic patients and showed beneficial effects, including improved glucose control via decreased HbA1C, decreased blood pressure, decreased CRP, decreased triglycerides, and increase in high-density lipoprotein compared to control group patients [42]
