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These derivatives play pivotal roles in immune cell biology
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HPLC-HRMS analysis Reversed-phase chromatography was performed using a Vanquish HPLC system controlled by Chromeleon Software (ThermoFisher Scientific) and coupled to an Orbitrap Q-Exactive HF mass spectrometer controlled by Xcalibur software (ThermoFisher Scientific), or by a Dionex Ultimate 3000 HPLC system coupled to an Oribtrap Q-Exactive mass spectrometer controlled by the same software
As previously stated, myoglobin-induced formations of potent vasoconstrictors F2-isoprostanes and ET-1 are among the mechanisms of renal toxicity induced by the use of methamphetamine use [106, 107]
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