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Pharmaceutics 13 (3), 381
Impairment of autophagy may be associated with follicular miniaturization in androgenetic alopecia by inducing premature catagen
Of note, the production of cellular oxidants is compartment specific, but their targets can be local or/and remote from the source compartment
Wilkinson et al
Oxidative stress activates NUPR1 by both ER stress (METH [79] and H2O2 [80]) and non-ER stress pathways, NUPR1 regulates ferroptosis via iron metabolism, ROS homeostasis, and the GSH/GPX4 pathway [81, 82]
