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Prokinetic agents such as metoclopramide or domperidone, which accelerate gastric emptying, may counteract some of the therapeutic effects of semaglutide on satiety and weight loss
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Additionally, NNMT has been shown to play a causal role in the development of T2D through quantitative trait locus mapping in mice (Yaguchi et al., 2005)
Journal of Physiology-Paris
