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MD Patrick Tyrance, Jr
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This review focuses on advances in therapeutic peptide brain delivery as liquid formulations and dry powder inhalers (DPIs), besides highlighting the role of IN-delivered high molecular weight molecules (including peptides) in treating various systemic diseases
Three-month old male mice were given 10 g IN-PACAP daily for 3 months, which stimulated nonamyloidogenic processing to lower A expression, and lowered BDNF and Bcl-2
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