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Description
Depending on dose, a fraction of APAP is converted into a highly reactive toxic intermediate, N-acetyl-p-benzoquinone imine (NAPQI) by several P450 cytochromes
Dihydroartemisinin inhibits the development of colorectal cancer by GSK-3/TCF7/MMP9 pathway and synergies with capecitabine
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Based on this finding, the research team proposed a new strategy for inhibiting the glutathione metabolic pathway to treat IDH1 mutant glioma
Oxidative stress has also been shown to increase aldehyde and AGE formation (137,138)
