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Epub 2014 Aug 5 Sutcliffe P, et al

Compared with other forms of carnitine, PLC exhibits a special affinity for muscle tissues, including those of the heart and skeletal muscles.* GPLC is a powerful antioxidant that scavenges free radicalsprotecting against lipid peroxidationassists in energy productioncontributing to proper carbohydrate metabolism, improved muscle function, and reduced lactic acid buildup during low-oxygen conditions, such as exerciseand provides powerful support for peripheral arterial blood flow

Therefore, optimal analysis tools should be developed for the assessment of potential immunogenicity in the preclinical or earlier stage

Heterogeneity intrinsic to each PAIS represents a major obstacle to the design and implementation of clinical trials

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