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Arthritis Rheum: Official Journal of the American College of Rheumatology (2000) 43(7):156070

Furthermore, studies in NAFLD patients reveal alterations in the expression and activity of key enzymes governing bile acid synthesis and metabolism

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The pituitary adapts to sustained stimulation, and receptor desensitization reduces efficacy over time

They reverse pigmentation in the skin and prevent melanogenesis, the effect of evening out skin tone by regulating the deposition of melanin in the skin
