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Combined epidermal growth factor receptor and Beclin1 autophagic protein expression analysis identifies different clinical presentations, responses to chemo- and radiotherapy, and prognosis in glioblastoma

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DNMT1 maintains established methylation patterns during DNA replication, ensuring stable gene repression across cell divisions, while DNMT3A and DNMT3B facilitate de novo methylation, which is crucial during early development and cellular differentiation (Jin and Liu 2018