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The in vivo neuron-to-astrocyte lactate shuttle in human brain: evidence from modeling of measured lactate levels during visual stimulation

greater than 100,000 RAE, which are usually accidental Chronic vitamin A toxicity may occur when large doses greater than 30,000 RAE are consistently taken over a long period of time, like months

McFarlin BK, Curtis JH, du Preez HN, McFarlin MA

In the canonical Wnt pathway, extracellular Wnt ligands trigger intracellular signaling events that stabilize -catenin , allowing it to translocate into the nucleus and activate transcriptional programs controlling cell fate and metabolism
