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10.1111/cen.13171 Clin Endocrinol
The disturbance of endoplasmic reticulum Ca2+ triggered by oxidative stress may also induce UPR and apoptosis ( + T cells to produce adaptive immune response, and T cells release interferon- (INF-), It binds to receptors on keratinocytes, further releases and presents inflammatory cytokines such as CXC-L16 and IL-15, and further recruits T cells to the skin through a positive feedback loop ( + and T cells induced by cytokines and chemokines ensure the final destruction of epidermal melanocytes (Figure 1)
Ngn nga qu trnh hnh thnh melanin t da c ti to trng sng hn
In addition, ferroptosis inhibitors, such as iron chelators, reactive oxygen scavengers and antioxidant stressors, although their effects are limited, they can still inhibit the neurodegenerative cascading response of Alzheimers disease-related injuries to a certain extent
A lower redox index was found in the POAG patients than the age-matched controls [86]
