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When specifically used for skin regeneration or remodeling, as the new blood vessels form, blood flow is increased into damaged tissues which promotes angiogenesis and that aids in wound/skin healing.GHK-Cu creams applied to facial, eye, and thigh skin show increased skin density, thickness, collagen production, and reduced wrinkles

To exert these apparent effects, CJC-1295 appears to interact with specific binding sites on the GHRH receptor protein, leading to conformational changes in the receptor structure and potentially initiating a cascade of molecular events

Wu DM, Lu J, Zhang YQ, Zheng YL, Hu B, Cheng W, Zhang ZF, Li MQ

[DOI] [PMC free article] [PubMed] [Google Scholar] 210.Kang D.W., Adams J.B., Coleman D.M., Pollard E.L., Maldonado J., McDonough-Means S., Caporaso J.G., Krajmalnik-Brown R